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FSS Caffeine Liposome
FSS Caffeine Liposome


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Starting at:$29.38

Product Code: FSS60131PF

FSS Caffeine Liposome:
2 oz
8 oz
1 kg (2.2 lbs)

FSS Caffeine Liposome PF
Preserved with Leucidal Liquid
Xanthine alkaloids such as caffeine increase microcirculation and fat metabolism. By increasing microcirculation, one can reduce swelling and achieve a slimming effect. Increasing fat metabolism correlates to a reduction in adipose tissue in fat chambers that contribute to the appearance of cellulite. As a result, formulators frequently use caffeine in products designed to have slimming and anti‐cellulite effects. When added to formulations, the antioxidant properties of caffeine can also help protect other actives in the formula. The antioxidant properties of caffeine protect the skin from extrinsic aging, as it is capable of scavenging hydroxyl groups (.OH) of free radicals with a reaction rate of 5.9 x 10(9) M‐1 sec‐1. This reaction rate illustrates that caffeine is comparable to other .OH radical scavengers.

Studies have shown that Caffeine is also useful for increasing photoprotection and treating atopic dermatitis. A study funded by the Laboratory for Cancer Research investigated the benefits of topically applied caffeine and reported that after a twice weekly UVB exposure for 20 weeks, SKH‐1 hairless mice that were treated with caffeine had a decrease in the occurrence of malignant and nonmalignant skin tumors by 44% and 72% respectively. Other research involving 83 patients published in Dermatology has shown that the topical application of caffeine effectively treats the symptoms associated with atopic dermatitis. It is hypothesized that the topical application of caffeine elevates levels of cyclic adenosine‐3’,5’‐monophosphate by inhibiting phosphodiesterase. FSS Caffeine Liposome contains 1% Caffeine. By incorporating it into a liposome we can enhance the delivery of caffeine to maximize its efficacy. We suggest formulating with 1 to 10% FSS Caffeine Liposome in cosmetic and personal care applications.

INCI Nomenclature:

Water & Phospholipids & Caffeine

Suggested Use Levels:



Skin Care


Liquid Liposomal Dispersion

pH (Direct):


Storage: Protected from direct light and humidity at a temperature of 50°-77°F (10°-25°C)
Shelf life: 12 months, properly stored, in sealed container.

This product should be added to a formulation at the recommended usage rate.


1) Shi, X. et. al. Antioxidant behaviour of caffeine: efficient scavenging of hydroxyl radicals. Food Chemical Toxicology. 1991 Jan;29(1):1-6.

2) Lehman Cullman, Susan. et. al. Topical applications of caffeine or (-)-epigallocatechin gallate (EGCG) inhibit carcinogenesis and selectively increase apoptosis in UVB-induced skin tumors in mce. PNAS. September 17, 2002. vol. 99. no. 19 12455-12460.

3) Kaplan, R.J. Topical use of caffeine with hydrocortisone in the treatment of atopic dermatitis. Archives of Dermatology. Vol. 114 No. 1, January 1978

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