FSS MicroVector Plump Southernwood HYA OS
Oil Soluble

BACKGROUND
Aging is a process that occurs
naturally and with aging comes changes in skin properties including morphology,
physiology and mechanical properties. These changes result in the appearance of
fine lines or wrinkles on the face, neck, hands, and upper arms. The amount of
wrinkles found varies from person to person depending on factors such as sun
exposure, lifestyle and diet.
The skin is made up of three layers:
the epidermis (outer layer), the dermis (middle layer) and the subcutaneous
tissue (fatty bottom layer). As a person ages all three of these layers go
through considerable transformations but the most significant changes occur in
the top two layers. The epidermal cells become thinner causing noticeable
difference in the transparency and the moisture of the skin. The dermal layer
also thins but this is due to the degradation of collagen and elastin, two of
its most important components. The loss of these materials cause skin to lose
elasticity and to wrinkle and sag. Skin firmness depleting as one ages is due
to the loss of collagen and elastin, skin proteins that are responsible for
elasticity, tone, and texture. While we cannot turn back the clock, skin care
products that provide anti-aging benefits can give consumers a revived and
youthful aesthetic.
SCIENCE
FSS MicroVector Plump
Southernwood HYA OS utilizes the
water-binding properties of hyaluronic acid to absorb water from the skin,
causing them to plump and fill in the appearance of wrinkles. MicroVectors are
composed of dehydrated components of the extracellular matrix interspersed with
silica microparticles in an anhydrous carrier to create an opaque gel. In the MicroVectors
system, the silica vectors help to deliver protein components to the newly disordered extracellular matrix. This
silica transfer system allows the ‘microvector’ to penetrate the skin and
deliver the active. When the microvector makes contact with water, it is able
to hydrate and swell therefore mimicking the biological ordering of the
extracellular matrix and decrease the appearance of wrinkles.
BENEFITS
FSS
MicroVector Plump Southernwood HYA OS effectively moisturizes skin and visibly reduces the appearance
of fine lines and wrinkles to fight the signs of aging while also smoothing
skin. FSS MicroVector Plump Southernwood HYA OS utilizes the
water-binding properties of hyaluronic acid to absorb water from the skin,
causing them to plump and fill in the appearance of wrinkles. MicroVectors are
composed of dehydrated components of the extracellular matrix interspersed with
silica microparticles in an anhydrous carrier to create an opaque gel. In the
MicroVectors system, the silica vectors help to deliver protein components to
the newly disordered extracellular matrix. This silica transfer system allows
the “microvector” to penetrate the skin and deliver the active. When the
microvector makes contact with water, it is able to hydrate and swell therefore
mimicking the biological ordering of the extracellular matrix and decreasing
the appearance of wrinkles.
EFFICACY
An in-vivo skin smoothing study was
performed to determine an increase in skin smoothness using FSS MicroVector
Plump Southernwood HYA OS. This study was based on comparing silicone
impressions that were made of the test sites before and after the 30 day, twice
daily, treatment on 20 (M/F) subjects between the ages of 38 and 53. Two areas
on the subject’s cheeks as well as two areas along the outer eye were selected
for the trial. The results in Figure 1 indicate that FSS MicroVector Plump
Southernwood HYA OS is capable of reducing the appearance of Crow’s feet by
12.0% and reducing the appearance of wrinkles on the cheeks by 4.0%.after the
study period. An 11-person, in-vivo study was
performed to evaluate the impact of the FSS MicroVector Plump Southernwood
HYA OS on stratum corneum moisturization. Initial stratum corneum values
were measured prior to the application of the test product for baseline values.
Measurements were then taken 1 hour after FSS MicroVector Plump Southernwood
HYA OS was applied. As illustrated in Figure 3, a 12.4% increase was seen
1-hour post application indicating that FSS MicroVector Plump Southernwood
HYA OS is capable of increasing stratum corneum moisturization. FSS
MicroVector Plump Southernwood HYA OS may be added to anhydrous systems to
effectively increase epidermal moisture.

Another in-vivo study was conducted to assess the
effects that FSS MicroVector Plump Southernwood HYA OS has on skin
characteristics, such as tone, elasticity, fine lines and wrinkles. 20 (M/F)
subjects applied a lotion containing 4.0% FSS MicroVector Plump Southernwood
HYA OS to their face twice daily for 60 days. The results in Figure 2
indicate FSS MicroVector Plump Southernwood HYA OS is capable of
increasing epidermal tone by 91% while improving epidermis elasicity by 63%. FSS
MicroVector Plump Southernwood HYA OS also decreased the appearance of
crow’s feet by 12% while decreasing fine lines and wrinkles on the cheeks by
10%. FSS MicroVector Plump Southernwood HYA OS can be recommended to
increase skin tone and elasticity for anti-aging benefits.

INCI Nomenclature:
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Ethylhexyl Palmitate & Silica Dimethyl Silylate &
Artemisia Abrotanum Extract & Butylene
Glycol & Phenoxyethanol & Caprylyl Glycol &
Hexylene Glycol & Sodium Hyaluronate
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Appearance:
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Brownish - Viscous, Translucent Liquid
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Solubility:
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Oil
Soluble
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Suggested Use Levels:
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2.0-4.0%
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Applications:
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Hydrating, Anti-wrinkle, Improves Skin Characteristics
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Storage: Protected from
direct light and humidity at a temperature of 50°-77°F (10°-25°C)
Shelf life: 12 months, properly stored, in sealed container.
This product should be added to a formulation at the recommended usage rate.
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References 1) Fuchs, E. 1998. Harvey Lectures. Beauty is skin deep: the fascinating biology of the epidermis and its appendages. 94:47-77. 2) Midwood et al. 2003. The International Journal of Biochemistry & Cell Biology. Tissue repair and the dynamics of the extracellular matrix. 36(6):1031-1037
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