FSS Phyto-Biotics Pumpkin Seed
Preserved with Leucidal Liquid SF
The demand for stem cell technologies has grown exponentially in the last decade. Trending specifically in the cosmetic market, current stem cell technologies utilize Meristematic cells, non-differentiating plant stem cells from simple cell extracts, with no specific activity. To propel beyond the current offerings on the market, we opted to use biotic stress, embodied by the sustainable practice of co-culturing of plant stem cells with Pseudomonas sp., to promote the formation of secondary metabolites. This novel approach induces cellular differentiation and provides formulators with the ability to finely customize formulations, specify activity and skin benefits while offering brand distinction. Pumpkin-themed personal care products often focus on the enzymatic properties of this fruit, however, focus in on the activity of the phenolic compounds, like ferulic acid, can help build brand differentiation and provide formulas with alternative skin benefits. the specific activity of the phenolic compound, ferulic acid. FSS Phyto-Biotics Pumpkin Seed capitalizes on the specific activity provided by Ferulic Acid to provide formulators with a plant-derived, stem cell ingredient capable of imparting anti-aging, antioxidant, anti-wrinkle, and protectant benefits while enhancing ATP synthesis and cellular metabolism. This novel approach gives formulators the distinct opportunity of creating activity-specific products by using an advanced stem cell technology.
Since pumpkin is loaded with antioxidants and nutrients, it is a formidable, yet gentle ingredient perfect for anti-aging products. Rich in vitamins A and C, pumpkin will help soothe and soften skin as well as repair free radical and environmental damage. Pumpkin also contains natural enzymes and alpha hydroxy acids, so it aids in removing dead skin cells on the surface and increasing cell turnover, thereby giving skin a smoother and brighter appearance. Good for hydrating dry skin due to its essential fatty acids, pumpkin can be just as beneficial in controlling excess oil and fighting acne since it is a rich source of the minerals copper and zinc as well as vitamin E. Pumpkin is a widely cultivated vegetable used for human consumption and in traditional medicine. Its extracts (from different parts of the plant) contain biologically active components which show antibacterial, antioxidant, anticancer activity, and other miscellaneous effects. In recent years, there has been a growing interest in studying the phenolic compounds of oilseeds because they represent potentially health-promoting substances. However, despite the ubiquitous presence of phenolic acids in plant-based food, and their role as antioxidants, literature regarding the presence of phenolic compounds in Pumpkins was limited. The most abundant phenolic acid present in pumpkin is p-hydroxybenzoic acid, but other phenolics, like ferulic acid, are also copious.
Research shows that plant stem cells can slow skin aging by defending against extrinsic stress, keeping skin looking youthful, longer. This discovery opened the door in cosmetic stem cell research and provided technological advances in the cosmetic industry, as there are no ethical controversies over the use of plant stem cells in contrast to the use of embryonic stem cells. Phenolic, or secondary, metabolites are organic compounds that have no fundamental role in the maintenance of the life process of plants. However, these compounds are essential for the plant to interact with its environment, allowing for adaptation, defense and ultimately the ability to survive in less than ideal conditions. Secondary metabolites are organic compounds that have no fundamental role in the maintenance of the life process of plants. However, these compounds are essential for the plant to interact with its environment, allowing for adaptation, defense and ultimately the ability to survive in less than ideal conditions. Examples of plants producing secondary metabolites can be found in a plant’s floral scent and pigment that have evolved to attract pollinators, enhancing fertilization rates. Some plants are able to synthesize toxic chemicals to ward off pathogens, herbivores or to suppress the growth of neighboring plants. Meanwhile, chemicals found in fruits prevent spoiling and send signals in the form of color, aroma and flavor to animals that eat the fruit and help disperse the seeds.
Supported by a plethora of studies, the secondary metabolites produced by pumpkins are potent antioxidants, protectants and Reactive Oxygen Species (ROS) scavengers. The secondary metabolite, or phenolic metabolite, of interest from Pumpkin Seed is Ferulic Acid. Ferulic Acid readily forms a resonance stabilized phenoxy radical, acting as a potent antioxidant and ROS scavenger. Implicated in DNA damage and the acceleration of cell again, ROS and free radicals are two extrinsic sources of stress from which the skin needs protection.
The destruction of plants continues to pose a major threat to the plant species. Commercially, the medicinal and cosmetic use of plant secondary metabolites involves isolating these organic compounds through solvent extraction of the naturally grown, whole plant. With the possibility of extinction at any given time, the development of alternative and complimentary methods to whole plant extract for the production of these organic compounds, particularly for commercial purposes, is an issue of considerable socioeconomic importance. By using cell cultures, industries can grow numerous plants, creating a sustainable source of plant extracts without disrupting the environment. As previously mentioned, using solvent extraction from a naturally grown, a whole plant is environmentally damaging. In order to sustainably source the necessary phenolic metabolite, Ferulic Acid, Cucurbita Pepo seeds are grown in cell culture. Using biotic stress, specifically pathogenic stress via Lactobacillus, our formulators created FSS Phyto-Biotics Pumpkin Seed by inducing the production of the phenolic compound, Ferulic Acid, to create a plant stem cell product capable of imparting anti-aging, antioxidant, anti-wrinkle, and protectant benefits while enhancing ATP synthesis and cellular metabolism.
INCI Nomenclature: Water & Cucurbita Pepo (Pumpkin) Cotyledon Extract
Appearance: Slightly Hazy to Hazy Liquid*
Suggested Use Levels: 1.0-10.00%
Suggested Applications: Anti-aging, Antioxidant, Anti-wrinkle, Stem Cells
pH: 6.0-7.0
Storage: Protected from direct light and humidity at a temperature of 50°-77°F (10°-25°C)
Shelf life: 12 months from the date of manufacture.
This product should be added to a formulation at the recommended usage rate.
All products sold are cosmetic grade; External Use Only; Cosmetic & Personal Care Formulations Only.
Our products are for cosmetic and personal care formulations only; External Use Only. We recommend working with a chemist or a formulator if you’re not advanced in formulating.
Statements contained herein have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat and cure, or prevent disease.
