FSS Turmeric Liposome PF has been developed to effectively deliver the benefits of turmeric
FSS Turmeric Liposome PF
Background:
Turmeric, or Curcuma longa, is one of the most well-known, widely researched, and commonly used Ayurvedic spices in the world. Curcumin, the main biologically active polyphenolic compound found in turmeric, has a multitude of benefits for skin and hair care, with its historical use as an antiseptic, antioxidant, and anti-inflammatory. However, the application of curcumin is limited due to its water insolubility, instability and poor bioavailability. Using modern encapsulation technology, FSS Turmeric Liposome PF has been developed to effectively deliver the benefits of turmeric in cosmetic and hair care applications and promote a healthy, glowing aesthetic.
Ayurveda is an ancient wisdom of healing, prevention, and longevity that incorporates natural plant extracts into cosmetic products for the daily care of skin and hair. In Ayurveda, beauty is more than skin deep – the skin is perceived to be a mirror that reflects that health of the body. The plant extracts and natural substances formulated into Ayurvedic cosmetics possess biologically active ingredients to deliver therapeutic benefits such as healing infections, soothing inflammation, and enhancing circulation. Ayurvedic remedies are rooted in herbs, spices and other natural ingredients, with one of the most commonly used ingredients in Ayurveda being turmeric. Curcumin is the main biologically active component of turmeric, responsible for giving the spice its yellow color, and well known for its ability to possess anti-inflammatory and antioxidant effects.
Liposomes can be used in the delivery of various cosmetic materials, vitamins, and minerals throughout the body, typically to the skin, for an array of advantages. The liposomes may attach and fuse to the cellular membranes, releasing their contents into the target cells. Liposomes are microscopic vesicles that consist of an aqueous center with a phospholipid membrane. Phospholipids contain a glycerol bonded to two fatty acids and a phosphate group with a polar head. The fatty acid portion of this biomolecule is hydrophobic and is located toward the outside of the lipid bilayer whereas the phosphate group is hydrophilic and faces the aqueous interior. These phospholipid walls are identical to those that comprise other human cell membranes. Liposomes act as vehicles to transport nutrients to the cells through layers of skin and enhance delivery of active ingredients.
When non-encapsulated materials are placed on the skin a range of factors determine the fate of the material. Stability, solubility, lipophilicity, and size are all obstacles the active must overcome to penetrate the epidermal barrier. Liposomes, which resemble the basic structures of cellular membranes, create a more beneficial interaction with skin cells. The structure and amphiphilic nature allows the liposomes to penetrate the epidermal barrier and travel deeper than free materials to deliver the anticipated results.
Liposomes are readily compatible with epidermal surface lipids, the skin’s primary moisture barrier, as these epidermal lipids exist as lamellar bilayers. Lamellar bilayers require less moisture to maintain their structure. When a liposome fuses with the epidermal lipids, the epidermal lipid structure becomes overloaded with water and out of equilibrium. To restore equilibrium, the water and phospholipid, as well as the active loaded, are rapidly churned through the top cell layers of the stratum corneum. Enhanced delivery of the active occurs as it is rapidly carried down through the stratum corneum. Liposomes’ proven delivery system yields a multitude of benefits; enhancing the penetration of actives yielding increased efficacy, offering time release mechanisms, protecting and delivering otherwise unstable ingredients, and the ability to target specific cells.
BENEFITS
Incorporate FSS Turmeric Liposome PF into finished formulas to minimize inflammation while allowing the skin to readily absorb potent antioxidant properties for increased functionality. Reveal the natural glow of your skin with the purifying properties of turmeric. This ancient spice can be used to promote healthy looking skin and leave you with a flawless complexion. FSS Turmeric Liposome PF is an innovative ingredient that effectively delivers the benefits of turmeric and curcumin in cosmetic and personal care applications.
INCI Nomenclature: Water & Curcuma Longa (Turmeric) Root Extract & Phospholipids
Appearance: Liquid Liposomal Dispersion
Color: Light Tan to Orange
Solubility: Water Dispersible
Suggested Use Levels: 1-10%
Suggested Applications: Liposome Technology, Encapsulation Technology, Antioxidant Protection
pH: (Direct) 4.5-6.5
*DO NOT FREEZE*
May Sediment upon Standing; Mix Well Prior to Use
**Note: Product may change appearance if exposed to cold temperatures during
shipment or storage. If this happens, please gently warm to 45-50°C and
mix until normal appearance is restored.
Storage: Protected from direct light and humidity at a temperature of 50°-77°F (10°-25°C)
Shelf life: 12 months, properly stored, in sealed container.
This product should be added to a formulation at the recommended usage rate.
All products sold are cosmetic grade; External Use Only; Cosmetic & Personal Care Formulations Only.
References:
1. N. K. Gupta and V. K. Dixit, “Development and evaluation of vesicular system for curcumin delivery,” Archives of Dermatological Research, vol. 303, no. 2, pp. 89–101, 2010.
2. S. Mourtas, M. Canovi, C. Zona et al., “Curcumin-decorated nanoliposomes with very high affinity for amyloid-β1-42 peptide,” Biomaterials, vol. 32, no. 6, pp. 1635–1645, 2011.
3. W. Tiyaboonchai, W. Tungpradit, and P. Plianbangchang, “Formulation and characterization of curcuminoids loaded solid lipid nanoparticles,” International Journal of Pharmaceutics, vol. 337, no. 1-2, pp. 299–306, 2007.
4. Y. Malam, M. Loizidou, and A. M. Seifalian, “Liposomes and nanoparticles: nanosized vehicles for drug delivery in cancer,” Trends in Pharmacological Sciences, vol. 30, no. 11, pp. 592–599, 2009.
5. D. Wang, M. S. Veena, K. Stevenson et al., “Liposome-encapsulated curcumin suppresses growth of head and neck squamous cell carcinoma in vitro and in xenografts through the inhibition of nuclear factor κB by an AKT-independent pathway,” Clinical Cancer Research, vol. 14, no. 19, pp. 6228–6236, 2008.
6. R. L. Thangapazham, A. Puri, S. Tele, R. Blumenthal, and R. K. Maheshwari, “Evaluation of a nanotechnology-based carrier for delivery of curcumin in prostate cancer cells,” International Journal of Oncology, vol. 32, no. 5, pp. 1119–1123, 2008.)
7. V. Badmaev, M. Majeed, “Tetrahydrocurcuminoids (THC) as a Skin Bioprotectant”, Agro-Food-Hi-Tech, Jan.-Feb, pp.25-27 (2000)
9. www.tetrahydrocurcuminoids.com
10. E. Sikora, G. Scapagnini, and M. Barbagallo. “Curcumin, inflammation, ageing and age-related diseases”. Journal of Immunity and Aging. 2010; 7: 1.
Our products are for cosmetic and personal care formulations only; External Use Only. We recommend working with a chemist or a formulator if you’re not advanced in formulating.
Statements contained herein have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat and cure, or prevent disease.
