FSS Curezyme

The hair fiber is composed primarily of keratin proteins, which are rich in amino acids such as lysine and glutamine.1 These amino acids are integral to maintaining the structural integrity and mechanical strength of hair due to their ability to form crosslinked bonds.2,3 Over time, chemical treatments, heat styling, and environmental stressors degrade these natural protein networks, leading to weakened, brittle strands. To restore resilience, modern conditioning systems often rely on synthetic quaternary ammonium compounds, which provide immediate smoothing but can accumulate and contribute to long-term buildup, dullness, and scalp irritation.

FSS Curezyme offers a next-generation, quat-free solution by harnessing the power of Curamina®, a biomimetic active that emulates the function of an enzyme naturally involved in catalyzing protein crosslinking.4,5 Specifically, Curamina® mimics the enzymatic activity by forming covalent bonds between the amine group of lysine and the carboxamide group of glutamine. These bonds act as molecular “glue,” reinforcing the hair’s structure by bridging damaged sites and rebuilding a protein matrix. 

What makes this system unique is the optimized enzyme-to-protein ratio with FSS Hydrolyzed Vegetable Protein PF, a sustainably sourced blend of hydrolyzed corn, wheat, and soy proteins. The low molecular weight of these hydrolyzed proteins enables deeper penetration into the hair shaft and better surface interaction. Once Curamina® facilitates the formation of lysine-glutamine bonds, the hydrolyzed corn, wheat, and soy proteins are anchored in place and are able to mimic the natural crosslinking behavior found in healthy, undamaged hair. This targeted approach enhances tensile strength, elasticity, and resilience without the occlusive film-forming characteristics of synthetic polymers.

Benefits:

• Conditioning

• Strengthening

• Repairing

References:

1. Velasco, Maria Valéria Robles, et al. “Hair fiber characteristics and methods to evaluate hair physical and mechanical properties.” Brazilian Journal of pharmaceutical sciences 45 (2009): 153-162.

2. Oshimura, Eiko, Hiroshi Abe, and Rina Oota. “Hair and amino acids: the interactions and the effects.” Journal of cosmetic science 58.4 (2007): 347-358.

3. Cruz, Célia F., et al. “Peptide—protein interactions within human hair keratins.” International journal of biological macromolecules 101 (2017): 805-814.

4. Kim, Yun Seog, and Su Jin Park. “Application of transglutaminase for hair revitalization.” Journal of the society of cosmetic scientists of Korea 39.1 (2013): 25-30.

5. Li, Ziyuan, and Jing Xiao. “Repair of damaged hair protein fiber by jointly using transglutaminase and keratin.” Scienceasia 47.2 (2021): 195-201.

FSS20562

Vegetable Protein Keratinoligase