FSS Phytocoll PF

(Preserved with Leucidal Liquid)

Benefits of FSS Phytocoll PF

• Direct Animal Collagen Replacement

• Enhanced levels of Moisture

• Natural Alternative

BACKGROUND

In the early 2000’s when consumer recognition of animal rights and animal derivatives became elevated, high molecular weight proteins such as soluble collagen (in an animal derivative form) (~ 300 kD) were used as the building blocks of almost all quality cosmetics and personal care products. However ever-expanding support for animal rights and consumer awareness has all but eliminated incorporation of animal proteins into new cosmetic formulations.

The unfortunate elephant in the room was that these animal proteins were popular based on their efficacy, no one can deny they worked. This led to the need for a naturally derived soluble collagen to fill a market need. By extracting proteoglycan structural elements from yeast, an alternative to traditional collagen was developed. FSS Phytocoll PF was created to satisfy the desire for a conflict free, effective alternative to soluble collagen for use in high-end cosmetics.

SCIENCE

Soluble collagen serves as an excellent film former, this can be attributed to the relatively uniform amino acid content of mammalian collagen which allows for the formation of complex H-bonded water bridges that are able to tie moisture to the peptide backbone in a type of molecular “net”. Atypical of film formers, collagen does not present the standard greasy shielded sensation but rather a luxurious-feeling film. Binding moisture to the skin effectively has traditionally been the reasonfor collagen’s popularity.

Yeast can be defined as any fungus of the family Saccharomycetaceae that produces alcohol and carbon dioxide as byproducts of the fermentation process. Two species are principally used for commercial application, Saccharomyses cerevisiae, a top-fermenting yeast, and Saccharomyces uvarum, bottom fermenting, or lager yeast. Interestingly, on a cellular level yeast contain many of the same metabolic processes that can be seen in humans. Some strains of yeast have been used as vectors to produce human collagen in culture.

Much like the mammalian extracellular matrix, yeast contains a variety of high molecular weight proteins, which contain hydroxyproline-rich regions. In contrast to mammalian tissue these yeast-derived proteins exist conjugated with sugars, in the form of glycoproteins. The typical ratio of carbohydrates to protein is 3:1. Due to the presence of sugar groupings that exhibit an excess of hydroxyl groups, there is significantly more water bound to than with mammalian collagen.

BENEFITS

By lysing yeast cells, and isolating the hydroxyproline-rich glycoproteins through the use of molecular sieves, FSS Phytocoll PF was produced as an alternative form of collagen. FSS Phytocoll PF duplicates the aesthetics of mammalian collagen while delivering enhanced levels of moisture to the skin or hair without the associated issues of using an animal based product. This enhanced level of moisture binding ability can be attributed to the presence of the sugars, which are typically absent of mammalian collagens. FSS Phytocoll PF may be formulated as a direct 1:1 replacement for animal derived collagen products.

EFFICACY DATA

An in-vivo moisturization assay was conducted over a period of four weeks to evaluate the moisturizing ability of FSS Phytocoll PF. For Efficacy Data, Please request from us.

Our products are for cosmetic and personal care formulations only; External Use Only. We recommend working with a chemist or a formulator if you’re not advanced in formulating.

Statements contained herein have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat and cure, or prevent disease.